Product

A modern data & compute solution for biotech R&D.

Hundreds of biotechs use Latch to make data analysis faster, cheaper, more accessible, and instantly accelerate their R&D milestones.

Latch Software Platform showing NGS (RNA, DNA, etc.) fastq files that had been imported from Illumina BaseSpace

Make scientific decisions faster than ever.

Centralize and standardize all your data and computation into a single source of truth.

DataUnlimited Data StorageConnect your team's instruments & public -omics data sources.RegistryUnified DatabaseHarmonize all your samples and metadata with downstream results.WorkflowsAccessible -omics data analysisDevelop and automate your workflows to make -omics data accessible at scale.PodsFlexible AppsBuild dataviz apps for scientists (RShiny, Dash, Streamlit)Scalable NotebooksAccess cloud computers to share and reproduce comp-bio analysis. (190 cores, 1 TB ram, 8 GPUs)

Latch Data

A storage solution for modern R&D.

Connect your instruments, workflows, and reports into your own private workspace secured by Amazon s3.

Search.../20210710.MISEQ0111Folder, 401 MBCreatedCreated byExecution IDKindTags11/11/2021, 1:30 PMCrispy (Workflow)8DU59DA928D35FolderDataSequencer ImportsBulk RNA-SeqPipeline Outputsdaddy-realnessBaseSpace ImportsYost, et all.pdfFOXP2_protein.pdbFOXP2.2_protein.pdbproperties.xlxsDeSeq Report20210697.MISEQ0111MISEQ0111_S1_L001_R1_001.fastq.gzMISEQ0113_S1_L001_R1_001.fastq.gzMISEQ0112_S1_L001_R1_001.fastq.gzMISEQ0114_S1_L001_R1_001.fastq.gzMISEQ0111_S1_L001_R2_001.fastq.gzMISEQ0113_S1_L001_R2_001.fastq.gzMISEQ0112_S1_L001_R2_001.fastq.gzMISEQ0114_S1_L001_R2_001.fastq.gz20210696.MISEQ011120210695.MISEQ011120210691.MISEQ011120210687.MISEQ011120210683.MISEQ011120210693.MISEQ011120210689.MISEQ011120210685.MISEQ011120210681.MISEQ011120210694.MISEQ013120210690.MISEQ013120210686.MISEQ013120210682.MISEQ013120210692.MISEQ013120210688.MISEQ013120210684.MISEQ013120210680.MISEQ0131RRD-PCR.92910Data ID85DU020PA39PD3Key...Value...UploadExplore DatasetsAccessShare

“The increased accessibility to data has led us to generate new therapeutic targets.”

- CSO, RNA Therapeutics Biotech

Enterprise data security

Secure and private in your own cloud environment.

A HIPAA badge showing that the Latch Platform is HIPAA compliant

HIPAA

A SOC-II badge showing that the Latch Platfomr is SOC 2 compliant

SOC-II

Unlimited storage

Store any data, any size, from anywhere.

A diagram showing that the Latch software platform is able to import your data from Benching, Cloud Providers such as AWS, Azure, and Google Cloud and Illumnia BaseSpace

A simple and accessible way to see every piece of data your team generates. Import from Benchling, AWS, DropBox, GCP, or Azure.

Screenshot showing fastq DNA sequence files being uploaded to the Latch platform, as well as buttons to do S3 bucket mounting and importing from Illumnia BaseSpace
Fine-grained user permissions

Track and trace every single change.

Keep an audit trail of who did what, and when. Accelerate daily tasks and your FDA IND proposals alike.

Screenshot showing an ouput file of an execution of a bulk RNA-sequencing workflow on the Latch platform.Executions of a MAGeCK workflow on the Latch platform.
Invite unlimited users.

Manage your users' access and permissions.

Manage members and workspaces under your organization. Invite unlimited users with fine-grained access controls.

permissions
permissionspermissions
Loved by wet and dry lab.

Give scientists access to data, quickly

NGS files (FastQ, BAM, SAM, VCF, PDB) have default visualizations, such as FastQC, IGV, and Protein Viewer built on top, so you can inspect key insights in seconds, without having to ever leave the Latch platform.

previews of files that can be viewed on latch

Latch Registry

An integrated database to harmonize metadata

Never lose track of mission-critical metadata

Metadata on NGS files within Latch Registry.

“With Registry, you can tie all of the sequencing data, strain images, and metadata together in one place. It makes analysis much more comprehensive and enables both scientists and bioinformatics team interface with the same images, sequencing files, and metadata in a table-like format.”

Chris Baldock, Chief Data Officer, Metagen

A collaborative database

A shared database for the wet and dry lab

A familiar spreadsheet-like interface that is easy to edit and reference files stored in Latch Data. Embed images or links to reports in the table for quick interpretation of biological data and create parent-child relationships between tables.

Import of sequencing data and setting workflow parameters within Latch Data.
Sequencing File Organization at Scale

Organize raw instrument files with metadata

Catalog and link files on Latch Data with metadata in a table-like format which allows you to designate strong types to columns in tables to enforce standardization. And import bulk data via a spreadsheet like Excel or CSV

latch registry table close up screenshot
Plugs into your workflows

Connect code and pipelines to registry

Connect your pipelines to read and write to registry for better traceability. Use APIs to easily query for patient cohorts or key information.

latch registry table close up screenshot
Findable

Search and find data instantly

Effortlessly search and filter Registry tables to retrieve past data based on specific column and cell values.

latch registry table close up screenshot
Developer-friendly

Update data with Python API

Registry Python API allows for CRUD (create, read, update, and delete) operations on Registry tables. Read and write to Registry tables from a workflow or notebook environment

...

file_path = Path(file.local_path)
file_size = os.Path(file_path).st_size

tbl = Table(id="1234")
with tbl.update() as updater:
tbl.upsert_record(
record_name,
{
"File": file,
"Size": file_size,
}
)

...

Latch Workflow Manager

A Workflow Orchestration Platform for Scalable Analyses

Upload any bioinformatics workflow with flexibility. Empower scientists to self-serve workflows.

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Image one

“Our developer uploaded workflows to Latch that can analyze 100 curves at a time. And all scientists need to do is click a button on Latch. This saves an enormous amount of time, probably a day of work per scientist, 20 days a month of labor.”

Eszter N. Tóth, PhD, Senior Research Scientist, Etcembly

Get a user-friendly interface. No extra work.

Auto-generation of workflow interface

Latch SDK is a flexible Python SDK that enables easy portability from existing frameworks and languages to Latch.

Define tasks using pure Python functions and leverage the subprocess module to spawn child processes that execute scripts in any language.

@workflow
def my_workflow(
...
read: LatchFile,
amplicon_sequence: List[String],
quantification_window_center: Union[None, int] = -3,
...
):
...
Select FileReadAmplicon SequenceQuantification Window Center3Amplicon Sequence

Each parameter can be configured by altering its corresponding component (swapping a number field with radio options for common integer values), adding documentation (such as labels and help tooltips), and by changing its order and grouping on the page.

@workflow
def my_workflow(
...
read: LatchFile,
amplicon_sequence: List[String],
quantification_window_center: Union[None, int] = -3,
...
):
...
read:
A fastq file of sequenced reads
__metadata__:
display_name: Reads
appearance:
batch_table_column: true
detail: (.fastq, .fastq.gz)
placeholder: Select a file or input URL/URI...
amplicon_sequence:
The amplicon sequence(s) used for the experiment
__metadata__:
display_name: Amplicon Sequence
appearance:
placeholder: AATTGGCC...
quantification_window_center:
Center of quantification window to use within respect to the 3' end of the provided sgRNA sequence.__metadata__:
display_name: Quantification Window Center
appearance:
multiselect:
options:
- {name: Cas9, value: -3}
- {name: Cpfl1, value: 1}
- {name: Base Editors, value: -10}
allow_custom: true
Select FileRead(.fastq, .fastq.gz)Select a file or enter URL/URI...Amplicon SequenceAmplicon SequenceAATTGGCC...Quantification Window Center(Relative to 3' of sgRNA)Cpfl1 [+1]Base Editors [-10]CustomCas9 [-3]
Scalability

Specify arbitrary resource your workflow needs

Use single-line python task decorators to easily define resources available at runtime.

The framework starts at 2 CPUs and 4 GBs of memory and goes all the way to 31 CPUs, 120 GBs of memory and 1 GPU (24 GBs of VRAM, 9,216 CUDA cores) to easily handle all processing needs.

@latch.medium_gpu_task
def cas_offinder(
...
):


@latch.large_task
def nf_core_rnaseq(
...
):
...

Latch Pods

Scalable, on-demand cloud computers

Productivity and flexibility of a personal computer. Scale of the cloud.

PodsPodMy AppsTemplatesScanpy312A template with Scanpy dependencies for single-cell analysis in PythonCRISPRMITBlurgHaspBioV.0.0.2LeafCutter511Annotation-free quantification of RNA splicingSingle CellUse TemplatePlot and annotate Single Cell RNA-Seq dataDownloadsContributor32 last weekHaspBioMy TemplatesPublic Templates

“Our company is extremely exploratory, I wanted something extremely flexible. I was looking literally for an extension of my personal computer. I needed to be able to write my own code, the way that I know how to do it today, and to connect that to seamlessly memory and compute.”

Jonathan Hsu, Chief Technology Officer, Gensaic

Scalable resources on-demand

Start large cloud computers instantly

It’s that simple - select up to 93 CPU cores, 8 GPUs, 730 GiB RAM, and 16000 GB of storage and click “Launch”

screenshot showing pod storage options on latch
Accessible notebook environment

Run analyses in notebook environments

Built-in Jupyter Lab and RStudio to support Python and R analyses & bash terminals for command-line operations.

...or use it with your favorite IDE — connect to Pods via SSH from your local computers and integrate with a familiar IDE (VSCode, PyCharm, and more) .

screenshot showing notebook enviroment on latch
Reproducibility at its core

Save, share, and reuse compute environments

Once your Pod is set up with dependencies, scripts, and analyses, you can save a snapshot of your Pod into a Pod Template.

All members in the same team workspace can start a new pod from a template. Make pod templates “Public” to share it with the world, or re-use others.

ShinyCell and Immunarch R packages for single-cell analysis on the Latch Platform.
Be in charge of what you pay

Save cost with auto-shutoff

Fine-grained options to auto shutoff a Pod if there is no network activity to save cost

screenshot showing auto shutoff on latch

World-class Customer Support

More than just a platform – an analysis partner

Don’t take our word for it.

The thing with Latch is the customer service is brilliant. No matter how good a platform is, if the customer service is not good, you’re not going to use it. Latch responds right away to literally any question. It’s quite insane actually.”

Eszter Toth - Group leader of Genomics, Etcembly

The people behind Latch and the responsiveness is awesome. I have been very impressed with how fast they respond to us. It feels like we’ve got this entire LatchBio team at our fingertips to solve the problems we’re not equipped to solve. That definitely exceeded expectations.”

Jonathan Hsu - Chief Technical Officer, Gensaic

The support and onboarding we received from latch has been way beyond our expectations. The platform has been a great solution for our complex spatial biology data.”

Colin Ng - Vice President of Business Development, AtlasXomics

How we work with Partners

We take your scientific journey seriously.

With Latch, we map out your entire end-to-end drug discovery campaign. Our engineering team acts as an extension to your company and provides support to migrate all data, workflows, and notebooks upfront. For early-stage companies, our in-house bioinformaticians provide consulting services to get your first analyses up and running as fast as possible. That way, you have more time doing life-saving science, and less time worrying about cloud infrastructure set up.

Accelerate biological insights now

7-Day Free Trial

Access the leading data platform for biology.

  • A scoping call to map out your scientific workflows
  • Access a curated workspace customized to your assays and needs
  • Live 16/6 support with a Latch bioinformatics engineer
  • A hands-on onboarding session to train your team