Gene Editing Toolkit

Design CRISPR guides. Understand Gene Editing Experiments. Analyze Genome-Scale Screening Data.


Overview

Modular data infrastructure to engineer gene editing proteins and screen the genome.


Answer Biological Questions

  • Search for potential off-target sites of RNA-guided endonucleases


  • Quantify insertions, mutations and deletions from genome editing proteins


  • Identify important genes from CRISPR-Cas9 knockout screens


Join leading biopharma companies who engineer genomes on Latch

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Plug n play modular components with your existing infrastructure

Generate publication quality plots with AI in seconds

Experimental Flow

Genome Scale gRNA Design with GPUs

Scan the entire genome with accelerated hardware using Cas-OFFinder

List of data within Latch

Explore Off-Target Statistics with AI-enabled Plots

Summarize information about mismatches and off-target locations with custom visualizations accessible to bench scientists

Validate Editing Behavior of Single Guides with CRISPResso2

Expose CRISPResso2 to biologists with a graphical interface

Display the full suite of parameters for different types of editors and experiment designs.

Mount S3 / GCP buckets, integrate with Illumina Basespace, drag and drop from laptops, deploy custom upload scripts from local servers

List of data within Latch

Access the familiar CRISPResso2 HTML report to inspect editing behavior and visualize the distribution of alleles

List of data within Latch

Explore CRISPResso2 Results with AI-enabled Dashboards

Adapt gold-standard academic tools to the specific scientific needs of your teams. Programmable dashboards + rich graphical controls for scientists

Analyze Genome Wide CRISPR Screens

Identify important genes from large scale perturbation experiments with MAGeCK.

View a workflow graph to track progresss and inspect historic logs for compliance and troubleshooting

List of data within Latch

Access and explore your data in a Finder-like filesystem

List of data within Latch

Build plots and code transform blocks to manipulate statistics for bespoke biology

Looking for an easier solution?

Eliminate manual clicking and user error with an automated plotting solution for your lab.

7-Day Free Trial

Access the leading data platform for biology.

  • A scoping call to map out your scientific workflows
  • Access a curated workspace customized to your assays and needs
  • Live 16/6 support with a Latch bioinformatics engineer
  • A hands-on onboarding session to train your team